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US IPOs Gone Cold: Healthcare sector

IPOs Gone Cold is a series focusing on companies that planned to list but have gone into silent running or have recently changed their plans. The table is divided into three sections: filed, lapsed and withdrawn. 

Lapsed includes companies that had their prospectus approved by the relevant regulators, but their approval period has expired or companies that had considered a listing where there has been no update in six months. Withdrawn includes companies that have publicly withdrawn their IPO plans.

All data has been gathered by triangulating ION Analytics’ proprietary and aggregated intelligence, pipelines, and company information. This provides a series of actionable situations where the companies may either look to resume or adapt their listing plans, or explore alternative dealmaking avenues. For more information, check out Dealogic’s Market Analytics page.

This edition is focused on healthcare companies looking to list on US exchanges.


After an initial burst of activity, healthcare IPOs in the US are still on the slow lane, set to finish the quarter at their lowest point since 2012.

So far (up to 15 March), the sector has seen 10 listings worth USD 2.1bn compared to 24 IPOs worth USD 2.7bn in the same period last year and USD 2.6bn raised from 32 deals in 2022.

The current year figures are expected to be boosted by the ongoing USD 420m IPO of Peru’s Auna SAA and the USD 75m listing of NeOnc Technologies.

The USD 693m listing of KKR [NYSE:KKR]-backed BrightSpring Health Services [NASDAQ:BTSG] is the biggest deal year to date. This was followed by the USD 437m listing of CG Oncology [NASDAQ:CGON]. The USD 367m IPO of Kyverna Therapeutics [NASDAQ:KYTX], and the USD 201m float of ArriVent Biopharma [NASDAQ:AVBP].

Source: Dealogic

BrightSpring has not done well since listing and is down almost 30%. However, CG Oncology, Kyverna Therapeutics, and ArriVent have performed much better, up 118%, 28%, and 14%, respectively.

Apart from IPOs, the slowdown was also reflected in the follow-on segment which saw 127 transactions worth USD 16bn compared to 470 deals worth USD 37.8bn during the same period last year.

Some of the companies in the IPO pipeline include Israeli hearing assistance company Orcam Hear, US clinical-stage biotechnology company Treadwell Therapeutics, Swiss-US company specialised in longevity-focused therapies ImmuneAGE Bio, Washington-based single-cell sequencing company Parse Biosciences, Netherlands-headquartered provider of sleep diagnostic and monitoring solutions Onera Health, contract drug development and manufacturing firm SK Pharmteco, and Japan-based MaRI, among others.

And with 21 filed deals pending and 24 more in the pipeline, listing activity in the sector can still pick up this year.

Filed List

Company Company Geography Filing Date Potential Deal Value (USD m) Exchange
Lirum Therapeutics Inc United States 11-Mar-24 Nasdaq – All Markets
Jyong Biotech Ltd Taiwan (China) 07-Mar-24 NYSE Mkt LLC
Boundless Bio Inc United States 06-Mar-24 Nasdaq – All Markets
Aprinoia Therapeutics Inc United States 26-Jan-24 24 Nasdaq – All Markets
Zhengye Biotechnology Holding Ltd China 09-Jan-24 20 Nasdaq – All Markets
Wangdiqiyuan International Holdings LTD United Kingdom 06-Dec-23 Nasdaq – All Markets
Sequoia Vaccines United States 06-Nov-23 25 NYSE Mkt LLC
Aibafang Group CO Cayman Islands 30-Oct-23 Nasdaq – All Markets
Invea Therapeutics United States 20-Oct-23 75 Nasdaq – All Markets
MED EIBY Holding Co Ltd China 24-Feb-23 20 Nasdaq – All Markets

Withdrawn IPOs

Company Company Nationality Withdrawn Date Potential Deal Value (USD m) Exchange
Jinrong Holdings Ltd China 13-Dec-23 Nasdaq – All Markets
Carmot Therapeutics inc United States 11-Dec-23 100m Nasdaq – All Markets
Eleison Pharmaceuticals Inc United States 29-Jun-23 40m Nasdaq – All Markets

Lapsed IPOs

Company Company Nationality Last Filing Date Potential Deal Value (USD m) Exchange
Advanced Biomed Inc Taiwan (China) 18-Jul-23 113m Nasdaq – All Markets
WORK Medical Technology China 30-Jun-23 14m Nasdaq – All Markets
Cortigent Inc United States 07-Jun-23 15m Nasdaq – All Markets
MDNA Life Sciences Inc United States 25-Apr-23 13m Nasdaq – All Markets
New Ruipeng Pet Group China 23-Jan-23 100m Nasdaq – All Markets
Jupiter Neurosciences Inc United States 02-Dec-22 15m Nasdaq – All Markets
Regentis Biomaterials Ltd Israel 04-Nov-22 15m Nasdaq – All Markets
Alopexx Inc United States 06-Sep-22 15m Nasdaq – All Markets